In , the Phase 2 clinical studies were initiated for males experiencing ED, then progressed to the Phase 3 trials that supported the drug’s FDA approval. Common ones include: Flushing of the skin. Sildenafil Viagra. In , Pfizer scientists discovered that sildenafil, which also inhibits the PDE5 enzyme, caused penile erection in males participating in a clinical study of a heart medicine. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Tell your doctor if tadalafil is not working well or if you are experiencing side effects.Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Cialis lasts up to 36 hours in the body, while Viagra lasts 4–6 hours in the body. Both are taken 30 minutes before sex. Cialis can cause limb pain, while Viagra can cause vision change, rash. View images of tadalafil and identify pills by imprint code, shape and color with the Pill Identifier.

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