Side effects Side effects of oral ED medicines are often mild. Sildenafil may not be safe to take for people with certain medical conditions including: a past history of stroke or heart attack in the last 6 months retinitis pigmentosa an eye disease It can also interact with many other medicines, particularly nitrates used in heart disease , amyl nitrite and blood pressure medicines. Men with untreated ED had relatively low baseline scores for all aspects of sexual function measured again using a 5-point scale in the IIEF. Sildenafil at steady state, at a dose not approved for the treatment of erectile dysfunction 80 mg t. The mean steady state volume of distribution Vss for sildenafil is L, indicating distribution into the tissues. Avanafil Stendra. Many people have no side effects or only mild ones.Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide. This boosts blood flow and helps you get an erection from . About sildenafil (Viagra) Sildenafil is a medicine used to treat erection problems (erectile dysfunction). Sildenafil is also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). If you have erection problems sildenafil works by temporarily increasing blood flow to your penis when. There is help for ED, but the first step is consulting your doctor. The tips below may give you the assistance you need to discuss your concerns. Find the words that are right for you. Say some of these “icebreakers” to yourself, choose the one that feels most natural, and practice it aloud to yourself or with your partner before your appointment.

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