You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Tadalafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension to improve your ability to exercise. Symptoms may include sudden urges to urinate urgency , difficulty in starting urination hesitancy , a weak urine stream, and more frequent urination — especially at night. Tadalafil can be synthesized starting from D – tryptophan methyl ester and piperonal via a Pictet—Spengler reaction. Mechanism of action[ edit ] Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum. This medicine is also used to treat erectile dysfunction and signs and symptoms of BPH. It depends on the platform and insurance provider. · Adcirca Cialis Descriptions Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines .  · What is Cialis? Cialis is a brand-name prescription medication. It’s FDA-approved to treat the following in males:* erectile dysfunction (ED), a condition in which you can’t get or keep an. How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this .