CIALIS can cause your blood pressure to drop suddenly to an unsafe level if it is taken with any nitrate medication. What does this mean? Your doctor will discuss the best treatment plan for you. Do not take a double dose to make up for a missed one. It can also interact with many medicines, particularly nitrates used in some types of heart disease and blood pressure medicines.For the as-needed dose, plan to take Cialis at least 30 minutes before sexual activity, but bear in mind it may take as long as 2 hours to take effect. Also, Cialis requires sexual stimulation to. Here are five things to know about the new topical gel and how it can help if you’re struggling to get an erection: 1. It Targets the Problem and Works Quickly. Being a topical means MED How can I buy tadalafil? You need a prescription from a doctor to buy tadalafil. You can buy it from a store-based pharmacy or reputable online pharmacy with a prescription. Some people buy tadalafil online without a prescription. This isn’t a good idea, as you can’t be sure whether these pills contain the medicine or are counterfeit.