Before taking dapoxetine Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. Take care if you are a driver. Never give it to other people even if their condition appears to be the same as yours. Overall, dapoxetine 30 mg or 60 mg is clearly associated with greater perceived overall improvement in PE compared with placebo. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital.You are taking medications called Phosphodiesterase-5 Inhibitors such as Sildenafil, Tadalafil or Vardenafil. You have a history of dizziness from low blood pressure or have had fainting episodes before. Mood conditions such as depression, bipolar disorder, thoughts of suicide or harming yourself. Dapoxetine is a short-acting selective serotonin re-uptake inhibitor. Indications and dose. This review encompasses studies of dapoxetine pharmacokinetics, animal studies, human phase I, II and III studies, independent postmarketing and pharmacovigilance efficacy and safety studies and drug-interaction studies. Dapoxetine is a potent SSRI which is administered on demand 1–3 h prior to planned sexual contact.