This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines. What treatment approach do you recommend? Your provider might also do a physical exam. It also has side effects that delay ejaculation. Tramadol can become habit-forming when taken long-term. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.The dapoxetine/sildenafil combination therapy significantly improves the IELT values and patient reported outcome measures of PE patients who also suffer from ED. Although . Treatment for these patients should consider the drug–drug interaction between dapoxetine and PDE5 inhibitors such as tadalafil (Cialis) or sildenafil (Viagra). In Dresser study . Dapoxetine tablets. Dapoxetine is prescribed for the treatment of premature ejaculation. Take one tablet hours before you have sex. The most common side-effects include feeling dizzy or faint, and feeling sick (nausea). Drinking a full glass of water at the same time as taking the tablet can reduce these effects.