It lasts 4 to 5 hours, or longer if you have mild to moderate ED. Cialis tadalafil : This ED medication works with the same principle as Viagra, but lasts up to 36 hours. It might work longer if you have mild to moderate erectile dysfunction. How oral medicines differ Each oral medicine for ED has a slightly different chemical makeup. It depends on the platform and insurance provider. ED medications can cause side effects, and it’s crucial to have access to a medical provider if needed.heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Common tadalafil side effects may include: headache; flushing (warmth, redness, or tingly feeling); nausea, upset stomach; stuffy nose; or. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side.  · Cialis; Descriptions. Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where . How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this .

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