Cialis for daily use is a good choice if you have sex three or more times a week. In pulmonary hypertension it works by relaxing blood vessels in the chest. Likewise, if you experience side effects, we may recommend that you try a lower dose of Tadalafil. This means that after 36 hours it may still be in your system. Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses. PDE5 inhibitors only work in the presence of nitric oxide, which is released during sexual arousal, so you will need to be aroused for Cialis to work. Cialis is an orange-yellow, film-coated tablet in the shape of an almond.CIALIS for once daily use is a lower dose you take every day. • Do not take CIALIS more than one time each day. • Take one CIALIS tablet every day at about the same time of day. You may attempt sexual activity at any time between doses. • If you miss a dose, you may take it when you remember but do not take more than one dose per day. About this medication. TADALAFIL (tah DA la fil) treats pulmonary arterial hypertension (PAH), a condition that causes high blood pressure in the lungs. It works by relaxing your . Dosage range: mg to 5 mg. Frequency: once daily, regardless of the timing of sexual activity. Cialis’s recommended dosage when it’s taken as needed for ED is as follows. Dosage range: 5 mg to 20 mg. Frequency: one dose at least 30 minutes before sexual activity, with a maximum of one dose per day*.