Do not take a double dose or more than one dose per day to make up for a missed one. Both Tadalafil and Sildenafil are licensed and safe to use. If you are taking tadalafil for erectile dysfunction, your doctor will probably start you on an average dose of tadalafil and increase or decrease your dose depending on your response to the medication. Interestingly, Cialis has been more linked to improved self-esteem and other psychological factors than the other PDE5 medications. For this purpose, one dose works for up to 72 hours. Tadalafil may not be safe for people with certain medical conditions, including people who have had a stroke , have coronary heart disease or retinitis pigmentosa an eye disease.Does tadalafil’s price depend on the strength I use ( mg, 5 mg, 10 mg, or 20 mg)? The price of tadalafil may depend on the strength. Tadalafil comes in strengths of milligrams (mg), 5 mg. In general, a lower dose (5mg) that’s meant for daily use can cost around $20 to $32 per dose, and a higher dose (10mg and 20mg) meant for “as-needed” use . Pay undefined at Walmart with a GoodRx discount. That’s 94% off the retail price of $ Walmart. $ retail. Save 94% $ chevron_right. How much does Tadalafil (Cialis) cost? expand_more. The lowest GoodRx price for the most common version of Tadalafil (Cialis) is around $, 96% off the average retail price of $