This search was then manually cross referenced for all papers. If you feel faint or dizzy, do not drive and do not use tools or machines. The tablet has a bitter taste, so swallow it whole without chewing. Both actions use your pelvic floor muscles. Identifying sexual comorbidities e. Involving the partner during the initial and subsequent interviews is preferred to determine their view of the situation and the impact of PE and its treatment outcome on the couple as a whole.Dapoxetine, a new antidepressant, has been found to be safe and effective for the treatment of premature ejaculation, according to two major clinical trials. Dapoxetin is a . Dapoxetine is currently the oral drug of choice for on-demand treatment of PE. Keywords: Dapoxetine, premature ejaculation (PE), selective serotonin reuptake inhibitor (SSRI) . Premature ejaculation (PE) is a common male sexual disorder which is associated with substantial personal and interpersonal negative psychological consequences. .