The patients in studies had varying degrees of ED. Efficacy Results from Controlled Clinical Studies The effect on one of the major end points, maintenance of erections after penetration, is shown in Figure 6, for the pooled results of 5 fixed-dose, dose-response studies of greater than one month duration, showing response according to baseline function. If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. In a study of healthy male volunteers, sildenafil mg did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates. Sildenafil for pulmonary hypertension can also be known by the brand names Revatio and Grandipam. In these studies, involving about patients, analyses of patient diaries showed no effect of VIAGRA on rates of attempted intercourse about 2 per week , but there was clear treatment-related improvement in sexual function: per patient weekly success rates averaged 1.The average length of time Viagra lasts. On average, Viagra lasts between 2 and 3 hours before its effects start to diminish. Viagra can last up to 5 hours or longer depending on your dosage, your. Typical dosing for Sildenafil (Viagra) The typical dose is to take 50 mg of sildenafil (Viagra) by mouth, about 1 hour before sex, as needed. The maximum recommended dose is mg. Don’t take sildenafil (Viagra) more than once daily (at any dose). Written by Brian Leonard, PharmD, BCACP, BCGP. Sildenafil (Viagra, Revatio) is a moderately priced drug used to treat erection problems in is also used to treat pulmonary arterial hypertension, a serious heart and lung drug is more popular than comparable drugs. It is available in generic and brand versions. Generic sildenafil is covered by most Medicare and insurance plans, but .